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#1 03-07-2024 10:36:00
- hannahcole
- Membre
Transgene Mapping
For transgenic cell lines and transgenic animals generated via many methods, the integration site is random and in most cases not known. Integration of a transgene can disrupt an endogenous gene, potentially interfering with interpretation of the phenotype. In addition, knowledge of where the transgene is integrated is important for planning of crosses between animals carrying a conditional allele and a given Cre allele in case the alleles are on the same chromosome.
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#2 11-08-2024 04:11:53
- wolfeh
- Membre
Re: Transgene Mapping
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#3 11-08-2024 04:13:07
- wolfeh
- Membre
Re: Transgene Mapping
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